The paper examines how framing anthropogenic climate change (ACC) affects public perceptions, particularly in the context of organized ACC denial present in U.S. media and culture. Through an experiment, the study tests four positive frames aimed at promoting action on ACC—economic opportunity, national security, Christian stewardship, and public health—alongside a counter-frame of ACC denial. The findings reveal that exposure to the ACC denial message significantly undermines beliefs in ACC, the credibility of climate science, awareness of its consequences, and support for emission reduction, particularly influencing conservative individuals more than moderates and liberals.